Ovarian follicles are the essential units of female reproductive biology, each of which is packed with roughly spherical aggregations of cells found in the ovary. A Graafian follicle, or ovarian follicle, is present inside an ovary and is a minute cyst within which an egg, or ovum, develops. A Graafian follicle is a follicle that ruptures and releases its ovum when stimulated. Generally, women are born with many undeveloped follicles, each containing an immature ovum. As soon as puberty is attained and menstruation commences, one ovum matures each month inside its containing follicle. The follicle grows bigger and breaks at around day 14 of the cycle, discharging the ovum in a process known as ovulation.
The developmental cycle of a follicle goes through a range of follicle stages:
An ovary is subdivided into:
Mutually, blood and lymph vessels are found in the loose connective tissue of the ovarian medulla. In the cortical compartment, the oocytes are found within a variety of follicle stages. The sex hormones manipulate the primordial follicles to grow and a restructuring to happen. Consecutively, from the primordial follicles the primary follicles, secondary follicles, and tertiary follicles develop. Only a small percentage of the primordial follicles reach the tertiary follicle stage - the great majority meets their end in advance in the various maturation stages. Large follicles leave scars behind in the cortical compartment and the small ones vanish without a trace. The tertiary follicles get to be the largest and, shortly before ovulation, can reach a diameter up to 2.5 mm through a special spurt of growth. They are then termed ‘Graafian follicles’. Occasionally, a Graafian follicle is unsuccessful to shrink after the ovum is discharged, or may not release it in any way. This makes the follicle to stay full of fluid and to persist to grow into a follicular ovarian cyst. Usually, these cysts vanish after a number of weeks without any required You do not have access to view this node.
Graafian follicles are fluid-filled shell that surrounds and protects the developing egg cell inside the ovary during the menstrual cycle. Once the Graafian follicle has ruptured, it fills with blood, at times causing slight abdominal uneasiness. This blood is rapidly substituted by cells which are prosperous in fat, called luteal cells, and the follicle becomes the "corpus luteum." The luteal cells manufacture estrogen and progesterone and this is known as the luteal phase of the menstrual cycle. If pregnancy follows, the corpus luteum remains, but if there is no pregnancy, it starts to break down a few days before the start of the next menstrual bleed, ending up as scar tissue. Rarely, the corpus luteum may not break but becomes a blood-filled cyst, called a luteal cyst or corpus luteum cyst. These cysts are noramlly noticed in women experiencing fertility You do not have access to view this node.
When the follicle grows. it produces some hormones which reacts with the uterine wall to become thickened and to be filled with enormous blood. This change is a kind of preparation of the uterus to obtain the fertilized egg and to provide for the development of the future embryo.