Who should avoid Zyban?

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Zyban (bupropion) is an antidepressant in the aminoketone drug category used for ending the habit of smoking. Zyban is a type of generic formulation and is used to help individuals stop smoking by reducing cravings and various effects of withdrawal. Diverse brands of bupropion (Aplenzin, Budeprion, Wellbutrin) are used to treat major depressions and seasonal affected disorders. It comes as a pill and does not contain nicotine. The standard dose of Zyban is a 150 to 450 mg daily.

What is the history of Zyban?

Zyban's history is fascinating. Smokers who happened to be the users of the anti-depression medication Wellbutrin (bupropion hydrochloride) typically reported a lessening in the need for cigarettes. Through more testing, the drug was found to be effective in treating the smoking addiction, and helping the smokers quit smoking. GlaxoSmithKline "repackaged" Wellbutrin and marketed it because the smoking-cessation drug Zyban is not like nicotine patches or nicotine gum. If you intend to use the gum or patches, then you should avoid taking overdose of nicotine.  In the beginning when you have just started using Zyban, you continue smoking for first couple of days. Eventually though, you reach a quit-date, and stop smoking. The treatment of Zyban is also ended after couple of days when the urge to smoke has vanished.

How does Zyban work?

This medication is employed together with a program for ending the habit of smoking e.g. support cluster, and counseling. Bupropionl decreases your nicotine withdrawal symptoms e.g., restlessness, irritability, anxiety and your need to smoke. Bidding adieu to the habit of smoking lowers your risk of heart and lung disease, and cancer. This medication belong to a category of medicines called antidepressants. It's not known precisely how bupropion works to cut back the urges for smoking. But scientists believe that it works by restoring the balance of natural chemicals (neurotransmitters) within the brain.

Who should avoid using Zyban?

Zyban ought to be used cautiously in patients receiving medication for serious health problems as it can aggravate the risk of seizures. Monamine oxidase inhibitor (MAOI) must not be combined with Zyban as it can lead to severe side effects. Minimum of 14 days need to elapse between discontinuation of an MAOI and initiation of Zyban (bupropion). Zyban could have an effect on the action of Coumadin (warfarin). Norvir (ritonavir) is known to increase the breakdown and elimination of Zyban (bupropion). There aren't any adequate studies on the impact of Zyban in pregnant women. In one study, there was no distinction among Zyban and different antidepressants within the incidence of birth defects. Zyban is secreted in breast milk and hence should be avoided when you are nursing a baby. You must not take Zyban if you have:

• Epilepsy or a seizure disorder
• An eating disorder e.g., anorexia or bulimia
• If you are employing a second style of bupropion
• If you have suddenly stopped use of alcohol or sedatives (such as Valium).
• Zyban could cause seizures, particularly in individuals with sure medical conditions. Relate all your medical problems to your doctor

If you are having any of the following conditions, your doctor might have to regulate your Zyban dosage or order special tests: 

• A history of head injury, seizures, or brain or spinal twine tumor
• Heart disease, high blood pressure, history of heart attack
• Kidney disease
• Liver disease (especially cirrhosis); or
• Bipolar disorder (manic depression)

What are the side effects of Zyban?

The most common side effects of Zyban are agitation, dry mouth, insomnia, headache, nausea, constipation, and tremor. In some patients weight loss is observed. Seizures conjointly occur, particularly when the doses are on the higher side. Get emergency medical help if you have any of these signs of an allergic reaction: hives; problem breathing; swelling of your face, lips, tongue, or throat. Call your doctor directly if you have any new or worsening symptoms such as: mood or behavior changes, anxiety, panic attacks, hassle sleeping, or if you are feeling impulsive, irritable, agitated, hostile, aggressive, restless, hyperactive (mentally or physically), additionally depressed, or have thoughts regarding suicide or hurting yourself.

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